This technical report reflects the outcome of the mammalian toxicology experts’ meeting on general recurring issues noted during the EFSA peer reviews of pesticide active substances under Regulation (EC) No 1107/2009. The main issues identified were related to genotoxicity of products and principles of (Q)SAR and read-across. General presentations on the different EFSA guidance and EFSA developmental activities related to human health risk assessment of pesticides were given.

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