The provisional molecular approach, proposed by EFSA in 2013, for the pathogenicity assessment of Shiga toxin- producing Escherochia coli has been reviewed.
toxin (2)
Shiga toxin–producing Escherichia coli (STEC) infect more than 100,000 individuals each year and are a major cause of lethal food-borne infections (1, 2, 3). STEC produce two related toxins, Shiga toxin 1 (STx1) and 2 (STx2), which kill cells by bloc