John Points

"Thanks Clare for the quick reply. Yes - that's useful to know. When we've detected residues in cattle liver, sheep liver and a (single) case of raw milk they have been about 40/50 triclabendazole sulphoxide to triclabendazole sulphone, with…"

"Hi Clare,
Thanks for an interesting talk last Tuesday. I had a question, but it was a bit too analytical-navel-gazing for the general discussion and I missed catching you afterwards.
For the triclabendazole, did you measure the metabolites…"

Hi John,
Glad you enjoyed the talk on Tuesday - I thought the overall quality of information was excellent and found it easy to follow.
With the triclabendazole, the analytes were measured individually as triclabendazole, keto, sulphone and sulphoxide and summed. Similar to your findings, sulphone had the highest readings for longer than the other analytes, making in milk, for example, a difference of approx 10 days in withdrawal times. Heat did not change the fact that suphone still remained the highest analyte for the longest in the product. In fact with the low residue level of triclabendazole, where it wasn't detected in the milk, sulphone was the only analyte detected in the products where there was a presence of triclabendazole at the 'low' reidue levels...
I hope this helps and if you want to discuss further, please do not hesitate to contact me.
Kind regards,
Clare

Comments

Clare Power February 24, 2012 at 9:16am

Hi John,
Glad you enjoyed the talk on Tuesday - I thought the overall quality of information was excellent and found it easy to follow.
With the triclabendazole, the analytes were measured individually as triclabendazole, keto, sulphone and sulphoxide and summed. Similar to your findings, sulphone had the highest readings for longer than the other analytes, making in milk, for example, a difference of approx 10 days in withdrawal times. Heat did not change the fact that suphone still remained the highest analyte for the longest in the product. In fact with the low residue level of triclabendazole, where it wasn't detected in the milk, sulphone was the only analyte detected in the products where there was a presence of triclabendazole at the 'low' reidue levels...
I hope this helps and if you want to discuss further, please do not hesitate to contact me.
Kind regards,
Clare

This reply was deleted.